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Kvalitet och resultat - Ortho Center Skåne

och Approach population studies (//www.hjartarannsokn.is/index.aspx? Acetabular index är en uppskattning av mängden avvikelse mellan kavitetens tak användes förutom morfologisk information dGEMRIC T1- och T2-kartor, som molekylär brosksammansättning, dGEMRIC (delayed Gadolinium-enhanced WOMAC Lequesne Index Lequesne Index (¨Rescue¨ medicinering ej tillåten) Quality (dGEMRIC Index) Following Knee Joint Distraction or High Tibial Osteotomy by Nick J. Besselink, Koen L. Vincken, L. Wilbert Bartels, Ronald J. van Heerwaarden, Arno N. Concepcion, Anne C. A. Marijnissen, Sander Spruijt, Roel J. H. Custers, Jan-Ton A. D. van der Woude, Karen Wiegant, Paco M. J. The average dGEMRIC index refers to the longitudinal relaxation time in the presence of gadolinium-based contrast agent. Voxel-wise fitting of the dGEMRIC signal using the Levenberg-Marquardt nonlinear least-squares method with in-house developed software (R2015a, The MathWorks, Natick, MA, USA) produced a reconstructed T1 map. The delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) index is highly correlated to mechanical stiffness, and, although not as good as a direct mechanical measurement, the index can be used as The dGEMRIC index is highly correlated to mechanical stiffness. A generalized relationship was found to provide good correspondence across sources and regions. Use of the dGEMRIC index as a predictive measure of stiffness is possible, depending on the application's acceptable error.

Dgemric index

Methods 3D rendering of the cartilage surface using the techniques descried by Tamez-Pena [1] was applied to 3D dGEMRIC images of the knee. After computing the dGEMRIC Index for each voxel (313 um x 313 um x 3mm) from the 3D SPGR acquisition, the median dGEMRIC Index across the surface normal was The average dGEMRIC index refers to the longitudinal relaxation time in the presence of gadolinium-based contrast agent. Voxel-wise fitting of the dGEMRIC signal using the Levenberg-Marquardt nonlinear least-squares method with in-house developed software (R2015a, The MathWorks, Natick, MA, USA) produced a reconstructed T1 map. The dGEMRIC index is highly correlated to mechanical stiffness. A generalized relationship was found to provide good correspondence across sources and regions. Use of the dGEMRIC index as a predictive measure of stiffness is possible, depending on the application's acceptable error. Copyright (c) 2007 Orthopaedic Research Society.

However, adipose tissue has lower extracellular water (ECW) than lean tissue. The aims of this study were to measure In the knees with radiographic OA, the dGEMRIC index at baseline was lower than that in the knees without radiographic OA (P = 0.03).

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The patients were divided into two groups on the basis of their dGEMRIC index. This division was established by ﬁrst calculating the mean and SD of the dGEMRIC indices of all of the study cohort patients.

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PMID: 17427215 2011-04-15 The dGEMRIC index is highly correlated to mechanical stiffness. A generalized relationship was found to provide good correspondence across sources and regions. Use of the dGEMRIC index as a predictive measure of stiffness is possible, depending on the application's acceptable error. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is based on the theory that Gd-DTPA(2-) will distribute in inverse relation to cartilage glycosaminoglycan (GAG). T(1Gd) (T(1) after penetration of a 0.2 mmol/kg dose of Gd-DTPA(2-)) has been used as the dGEMRIC index, although (1/T(1Gd)-1/T(1o)) should be more representative of Gd-DTPA(2-) concentration (where T(1o) = T(1) before contrast). 2006-11-01 The dGEMRIC index was assessed on MRI according to established protocol. Regression analysis adjusted for age, sex, body mass index (BMI), and presence of clinical knee OA. Mean age and BMI were Delayed gadolinium‐enhanced MRI of cartilage (dGEMRIC) is based on the theory that Gd‐DTPA2− will distribute in inverse relation to cartilage glycosaminoglycan (GAG).

ABR, auditivt BMI, Body mass Index. BMJ, British dGEMRIC, gadoliniumförstärkt magnetisk resonansbildning av brosk. trastförstärkt MR (dGEMRIC), där man försöker mäta kvalitet på brosket, index-patellarsenorna noterades ett mer heterogent ECM med slumpmäs-.
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Interpretation — A traumatic cartilage injury is associated with a high prevalence of OA after 17 years. A recent study indicated that low dGEMRIC may predict future radiographic knee OA.43 The dGEMRIC index has been shown to be low in individuals with moderate to severe radiographic knee OA,15 after cruciate ligament injury44 45 and in diseased knee compartments on arthroscopy.46 In addition, a range of dGEMRIC values has been observed in radiographically comparable compartments demonstrating The dGEMRIC index (mean ± sd) at four times (min ± sd) after intravenous injection of double dose Magnevist. The dGEMRIC index was 20–30 % lower in the patients with early OA compared to healthy volunteers (P < 0.003) at all time points, with largest difference at the earlier time points due to faster wash-in of the contrast in the OA cartilage. Objective To determine the association between changes in the delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) index over 2 years as a measure of cartilage proteoglycan concentration, with changes in cartilage thickness in the medial tibiofemoral compartment of knees in middle-aged women. Methods One hundred and forty-eight women (one knee for each subject) aged ≥40 years were included dGEMRIC index, cartilage thickness, surface area, and volume for each of the four joint quadrants and compared the manual and the automated 3-D analyses using mean differences.

ized, longitudinal study51 that compared the dGEMRIC index of patients with FAI undergoing surgery with those treated nonoperatively. The following inclusion criteria were used: the presence of hip pain; radiographic signs of skeletal maturity; AP radiographs; and the availability of both CT and MRI with dGEMRIC of the same hip joint. Similarly, in obese subjects, quadriceps strength was shown to correlate positively with dGEMRIC , as did weight loss . The implication of biomechanics in alterations in molecular metrics is further strengthened by the observation that knee malalignment has been shown to correlate to medial/lateral ratios of the dGEMRIC Index .
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Then patients were grouped according to whether they were less than one SD or at least one SD below the mean dGEMRIC index of 426 msec. To compare the delayed gadolinium-enhanced magnetic resonance (MR) imaging of cartilage (dGEMRIC) indexes acquired with different gadolinium-based contrast agents (GBCAs), with emphasis on the difference in electrical charge, and to evaluate the feasibility of the use of GBCAs other than gadopentetate dimeglumine with a double negative charge (Gd-DTPA 2−) as alternatives at dGEMRIC. Application of dGEMRIC to study clinical hip problems has focused on a single summary index describing the entire joint (3).

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Thus, a higher dGEMRIC index indicates healthier cartilage (Fig. 1) [ 59 ]. Similar to the knee [ 4, 34 ], dGEMRIC is a promising tool to quantify cartilage healing or degeneration before and after joint-preserving hip surgery and to monitor the natural course of hip diseases. The dGEMRIC index was calculated as the average of the T1 values for the acetabular and femoral head cartilages. Results: The dGEMRIC index correlated with both pain (rs = -0.50, p < 0.0001) and the lateral center-edge angle (rs = 0.52, p < 0.0001), whereas the joint space width did not correlate with either, with the numbers available.