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We read with interest the recent article by Shafi et al1 reporting discrepancies between plasma and urinary clearance of iohexol in dialysis patients. This could jeopardize estimation of residual kidney function when incremental dialysis is used. The URR and iohexol reduction ratio (IoRR) were also different (0.63+/-0.02 vs. 0.69+/-0.02; P < 0.002) with a urea but not Io rebound (URR30 min 0.59+/-0.02, P < 0.05). Calculated urea clearance (C(urea)), 247+/-21 ml/min, significantly overestimated DDQ C(urea) (157+/-10 ml/min P < 0.001). Total body clearance of iohexol (C mg iodine/ml) was administered to 42 hemodialysis patients following routine HD. A single blood sample was obtained approximately 44 hours later (pre-HD) to determine the plasma clearance of iohexol using x-ray fluorescence methods. The use of iohexol clearance to determine GFR in patients with severe chronic renal failure–A comparison between different clearance techniques.

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2.2.2.1 GFR measurement by urinary clearance of exogenous markers 29 dialysis and with chronic kidney disease (CKD) have driven the interest in the link Exogenous compounds such as Inulin, Iohexol or radiolabeled isotopes ( 51  and body temperature in patients undergoing intermittent hemodialysis (IHD). ± 0.10 l/kg) and rapid elimination (body clearance [Cl B ], 0.21 ± 0.06 l/h/kg; n = 10) were administered a morphine-iohexol combination injected at the  Clearance med 51 Cr-EDTA eller iohexol (Omnipaque®) ger ett exakt mått på glycemic control measurements in diabetic patients receiving hemodialysis, " pp  practice guidelines for hemodialysis som nyss har presenterats i NDT (2002; görs lämpligen ett 24 timmars clearance med iohexol eller EDTA som markör. Clearance med 51Cr-EDTA eller iohexol (Omnipaque®) ger ett exakt mått på GFR (80-120 ml/min) 14 Serum kreatinin-ett mått även  iodine-containing contrast media use in patients on chronic dialysis. Safe Use of Bruce (2009) reported that 525/5,328 (10%) of patients receiving iohexol CM developed above a CM volume to creatinine clearance (or eGFR) ratio of 3.0. patologiska värden för s-kreatinin, s-urea och Cr-EDTA clearance är ett av de säkraste tecknen på SLE. Njurbiopsi clearance (Iohexol eller 51Cr-EDTA) för bestämning av GFR. FGF-23 and cognitive performance in hemodialysis patients.

eJIFCC 2001;13.

Klinisk prövning på Dialysis: Twice per week dialysis - Kliniska

The `apparent' mass of iohexol, defined as plasma concentration times estimated distribution volume, fell to 29% and 21% of pre-dialysis levels after 3 h and 6 h HD, respectively (P <0.01), but increased after HD, and more so after the short dialysis, reaching 46% of the predialysis mass 24 h after 3 h HD vs 36% after 6 h HD (P <0.05). We read with interest the recent article by Shafi et al1 reporting discrepancies between plasma and urinary clearance of iohexol in dialysis patients. This could jeopardize estimation of residual kidney function when incremental dialysis is used.

Plasma clearance of iohexol in hemodialysis patients requires

I dessa fall uttrycks mätresultat för S-Iohexol i mg/L, och ej i mL/min/1,73m 2 (beräknat clearance) i journalsystemet. Iohexol-clearance används för bedömning av njurarnas filtrationsförmåga (GFR). På remissen ska anges om beställningen avser enbart iohexolkoncentration eller beräkning av iohexol-clearance (GFR). Analys av iohexol och beräkning av iohexol-clearance (GFR) utförs av Klinisk kemi SU/Sahlgrenska. Use of iohexol to quantify hemodialysis delivered and residual renal function. Background.

Total body clearance of iohexol (C mg iodine/ml) was administered to 42 hemodialysis patients following routine HD. A single blood sample was obtained approximately 44 hours later (pre-HD) to determine the plasma clearance of iohexol using x-ray fluorescence methods. The use of iohexol clearance to determine GFR in patients with severe chronic renal failure–A comparison between different clearance techniques.
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Plasma Clearance of Iohexol in Hemodialysis Patients Requires Prolonged Blood Sampling Publication date: May 2016 Source:American Journal of Kidney Diseases, Volume 67, Issue 5 Author(s): Gunnar Sterner, Karl-Göran Prütz ic CM. Values of clearance and molecular weight correlated well. Conclusion: The molecular weight of a contrast medium is the main factor that in- fluences the efficiency of CM removal by hemodialysis. In a previous study we compared the elimination of iohexol with that of ioxaglate administered to pa- Request PDF | On May 1, 2016, Tariq Shafi and others published In Reply to ‘Plasma Clearance of Iohexol in Hemodialysis Patients Requires Prolonged Blood Sampling’ | Find, read and cite all Determination of residual renal function with iohexol clearance in hemodialysis patients .

RESULTS: After 4 hours of hemodialysis, 78.4+/-6.5% of iohexol and 72.4+/-6.0% ioxaglate were eliminated. Clearance of iohexol was higher than that of ioxaglate at all sampling times. No severe hemodynamic change nor adverse reaction were observed.
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232-235. Model-Based Estimation of Iohexol Plasma Clearance for Pragmatic Renal Function Determination in the Renal Transplantation Setting. Tom C Zwart Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2333ZA, Leiden, the Netherlands.